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Did you know you can compare your DNA to Nicolaus Copernicus?

Identifying the skeleton of this world-famous astronomer

On his 540th birthday Copernicus received the highest of modern day honors, a Google Doodle. Yet he was buried in an unmarked grave for more than 450 years, because at the time of his death, Copernicus was only a little-known astronomer. This is a story of what happens when death precedes fame, and how DNA tests were instrumental to Copernicus finally receiving the hero’s burial he deserved.

Nicolaus Copernicus, the shining star of the Renaissance period, was the founder of modern astronomy. He was a highly intelligent scholar, and is remembered as an exceptional mathematician and astronomer. He was also a physician, classics scholar, translator, governor, diplomat and economist and even had a doctorate in canon law. Copernicus’ most important contribution to science was his heliocentric hypothesis – the idea that the Sun is at the center of the universe. This claim rocked convention because at the time it was popularly assumed that Earth was the center of the universe.

Statue of Copernicus in Warsaw, Poland
Statue of Copernicus in Warsaw, Poland

Copernicus had spent years of his free time making observations of the heavens by naked eye (because the telescope wasn’t yet invented), when he noticed that rearranging the planets to revolve around the Sun made “a harmonious relation between the size of the orbit and the planetary period”. This contradicted the commonly believed Ptolemaic system, in which the planets were said to revolve around Earth. His radical model was based on complex mathematical calculations, but Copernicus was hesitant to publish his book because he feared that “he would expose himself on account of the novelty and incomprehensibility of his theses.”

Finally in 1542, his friends managed to convince Copernicus to publish his book titled De Revolutionibus Orbium Coelestium (On the Revolutions of the Celestial Spheres). By this point, he was suffering from ill health. The legend has it that Copernicus was presented with the final printed pages of his book on the day he died at the age of 70 in 1543. He is said to have awoken from a stroke-induced coma to look at his book, and then died peacefully after saying his final farewell to his life’s work.

At the time of his death Copernicus wasn’t yet famous. His heliocentric theory hadn’t taken ahold, and it was years before Galileo was able to confirm the observation using the telescope. So, Copernicus was buried in an unnamed tomb in the Frombork Cathedral, Poland. His burial site was one of over 100 tombs in the cathedral and many others were also unnamed, which meant finding his remains wasn’t an easy task. Attempts were even made by Napoléon in 1807 to search for Copernicus’ grave.

One theory was that his tomb could be located near the St. Cross Altar, because Copernicus was in charge of the altar while he was a priest at the cathedral. In 2005, several skeletons were discovered near the St. Cross Altar, one of which was speculated to belong to Copernicus. The scattered bones on the incomplete skeleton belonged to a 60-70 year old man, the approximate age of Copernicus, and a facial reconstruction based on the skull showed a broken nose and other facial features that matched a self-portrait of Copernicus.

Skull of Copernicus
The skull of Copernicus. (Figure from Bogdanowicz et al. (2009) Proc Natl Acad Sci USA)

But the archeologists still had doubts as to whether they had found the right remains. For conclusive results, DNA was extracted from the skeletal remains, and compared to DNA from several hairs presumed to belong to Copernicus. These hairs were found in the astronomical reference book Calendarium Romanum Magnum that was used by the astronomer for many years.

The researchers chose mitochondrial DNA (mtDNA) analysis, as it is the most suitable for ancient remains, due to its high copy number (hundreds per cell), rapid evolution rate and strict maternal inheritance. There are three regions of the mtDNA genome that can be analyzed – two hypervariable non-coding regions (HVR1 and HVR2), and a coding region. The DNA profile (based on HVR1 and HVR2) from the skeletal remains was a perfect match to the DNA profile from the hair samples. Not only that, the mtDNA profile was extremely rare in existing databases, providing further evidence that the skeletal and hair samples are from the same individual.

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The perfect genetic match, together with the anthropological and archaeological information convinced the scientists that the skeletal remains indeed belong to Nicolaus Copernicus. In 2010, more than 500 years after his death, Copernicus was given the burial he deserved. His body was reburied in the same spot at Frombork Cathedral where his remains were found, but this time a black granite tombstone bearing a representation of Copernicus’s model of the solar system identifies him as the founder of heliocentric theory and a church canon.

This study defined the mtDNA HVR1 and HVR2 maternal lineage of Nicolaus Copernicus. If you have taken the DNA Maternal Ancestry Test, you can compare your DNA against Nicolaus Copernicus to see if you have descended from the same maternal lineage as this world-renowned astronomer.

References:

Bogdanowicz et al. (2009) Genetic identification of putative remains of the famous astronomer Nicolaus Copernicus. Proc Natl Acad Sci USA. 106(30):12279-12282.

Gingerich O. (2009) The Copernicus grave mystery. Proc Natl Acad Sci USA. 106(30):12215-12216.

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